Montepulciano is located in the center of that area of southern Siena which includes the Val d’Orcia the Valdichiana and, in part marginal, the Crete Senesi .
Therefore, those who stay overnight in Montepulciano can quickly reach the main cities of art such as Siena , Florence , Cortona , Pienza , Montalcino , San Quirico d’Orcia , Orvieto , Lake Trasimeno , the LIPU oasis of the lake of Montepulciano and the Etruscan tombs of Chiusi .